Yes, I found several relevant pieces of information about glycosylation in the Papers - Human Health database:
Glycosylation is a critical process in biology, where complex sugars (glycans) are attached to proteins and lipids, modifying their chemical properties1.
Glycans play essential roles in cell-cell communication, immune responses, and are altered in cancer cells. They are also exploited by pathogens to infect host cells7.
The complexity of glycans has made them challenging to study compared to DNA, RNA, and proteins. They can form variably branching structures depending on the presence or absence of numerous sugar-adding and -removing enzymes7.
Recent research has revealed that glycans are even present on RNA molecules, a surprising finding that expands our understanding of glycosylation7.
Glycosylation is crucial in the context of COVID-19, as glycans both shield the SARS-CoV-2 virus from the immune system and shape the spike protein as it attempts to enter cells7.
In pharmaceutical development, the ability to control glycosylation in cell-free systems is seen as a potential "game changer" for producing complex proteins like antibodies6.
These findings highlight the importance of glycosylation in various aspects of human health and disease, as well as its potential applications in biotechnology and medicine.